A newly metamorphosed sea urchin juvenile in which juvenile spines and pedicellaria are positioned with 5-fold radial symmetry (Davidson Lab)
Drosophila embryo cross-sections showing localized gene expression which specifies distinct tissues (Stathopoulos lab)
Tightly knit: A close-up on tissue-engineered cardiac muscle reveals an organized network of actin fibrils (green) that embeds the the cell nuclei (blue).
Jellyfish Muscle and Nerves
The jellyfish motor: Jellyfish swimming is powered by a single layer of muscle (green) and controlled by neurons (red). Eight lappet images were compiled to create the impression of a full body shot (J. Nawroth, Dabiri Lab).
Jellyfish in bloom: Time lapse of swimming pulsations in a juvenile moon jellyfish (J. Nawroth, Dabiri Lab).
Bacillus subtilis bacteria transforming from growing cells to dormant spores (Elowitz Lab)
Transgenic feeding sea urchin larvae, expressing a foxA regulatory gene construct in midgut (M. Cui, Davidson Lab)
Epigenetic marking and transcriptional changes across the genome through early T cell lineage commitment (J. Zhang, Rothenberg Lab)

Welcome

Systems Biology seeks to understand how the parts of biological systems are integrated to produce the amazing machines, cells, organisms and ecosystems that exist in our world.  We seek to define general principles of biological systems. Our goal is to train students who can seamlessly integrate diverse quantitative and experimental methodology and can balance the tension between global understanding and mechanistic insight.  This training involves study of biology, mathematics, quantitative reasoning, computational and data analysis tools, and the rich experimental methods of the biological sciences.

Announcements

We're starting a new exciting program in Systems Biology at Caltech! Prospective graduate students and postdocs are welcome to apply.